请选择 进入手机版 | 继续访问电脑版
.
 找回密码  注册
包子
论坛
bbs.baozi.su
论坛BBS首页大本营图片视频笑话社团联系我们
赞助商广告发布细则 电话89166258194(中) 84991302295(русский)
查看: 267|回复: 4

深藏奥义 基因与疾病不得不说的那些关系

[复制链接]
发表于 2017-5-8 03:33 | 显示全部楼层 |阅读模式
 
' C* x! W2 j5 j  X  什么是基因呢?基因是一个音译词,顾名思义,是基本因素的意思。对生命而言,它就是一个最重要的遗传信息载体。人类认识遗传现象已经有几百年的时间了,但是什么因素决定了遗传,这一问题在50年前才被解答,人们才知道基因是决定遗传的信息。它的化学物质是脱氧核糖核酸,是由四种不同的分子串联、排列组成的大分子。基因的功能非常关键,这里用四个简单的比喻,它是建造大楼的图纸,是长成参天大树的种子,是精彩演出的剧本,也是我们人体大脑指挥作战的司令部。/ T1 m# [  I9 D4 A6 I5 }

0 M4 X2 J; R8 x5 N1 u( n* i  人的疾病和基因又有什么关联呢?人生病有各种各样的因素,但不外乎于内因和外因两类。内在的因素最根本的就是基因,现在医学研究表明,所有的疾病或多或少都和基因有一些关联,主要是由于基因的改变、突变和表达的改变造成的,所以说为什么人会生病看来是个简单的问题,其实却是目前我们医学遗传研究学中最基本的问题。一般来讲,人体内大约有四万个基因,但不是说每个基因都是正常的,有些是有缺陷的,而这些有缺陷的基因往往成为致病基因。目前,一般来说看上去正常的、没有病的健康人,他身上都带有5个至6个致病基因,只不过他身体内还有一套正常的基因代替致病基因在起作用,因而致病基因没有表现出来。, U' z7 c% @$ p- l4 e! C

  l. G8 C. s- C2 R& o6 R! k  J- y深藏奥义!基因与疾病不得不说的那些关系 6 I8 |# W! k& }

  ~% ^! ^$ v9 a* D! m: i  我们常说的疾病其实是一种表象,比如说发热、高血压、糖尿病等等。而基因病是从基因的生理机制上把疾病的内在因素揭示出来,就是说最根本的因素是有一些基因缺陷,要想办法找到有缺陷的基因,然后为这种疾病的预防、诊断和治疗等等提供依据。
, u& v- X& Z( c( I" L; j& p1 V4 d1 y: A5 o0 K$ q% C6 ~4 c# f1 Q. j8 q' {
  由基因缺陷而导致的疾病广泛地讲就是基因病。过去治疗疾病有传统的方法和模式,比如说神农尝百草。而现在的医药治疗疾病就是从基因的角度找治疗的方法,比如说高血压,根据调节血压的一些基因来寻找抑制血压升高的小分子化合物。还有像现在的糖尿病和肿瘤都是根据基因的改变作为药靶来筛选药物进行治疗。当然这方面还有很多例子,基因药本身就可以用于治疗,比如现在有一种促进红细胞生成的药物,它可以治疗肾衰形成的贫血。在过去肾衰形成的贫血除了 外病人只能存活半年,现在有这个药后,病人可以存活20多年。高血压通过血管紧张素抑制这种药物就能治疗。所以说基因研究在药物当中的价值和作用是非常大的。基因是现代生物医药研究的先导、制高点和生长点,是一个核心。& s, |) m$ A- S# D

  ^$ x5 x5 m1 S1 Z  J* @  随着基因技术的飞速发展,人们从分子水平认识各种疾病的发生机制成为可能。研究发现,几乎所有疾病都与基因有关,是可以遗传的。一直以来,医学界将疾病分为遗传性疾病、非遗传性疾病。现在看来,这种划分已经过时。越来越多的研究证实,人类疾病的发生发展几乎都直接或间接地与基因密切相关。可以这么说,绝大多数人类的疾病都是基因病。因此,科学家一直不遗余力地寻找某基因和某疾病的对应关系。$ P. h# ^0 B$ a3 G/ W' C

8 e! R. O# B$ q$ S) u; _  基因病就是因为基因的突变,或基因的表达调控出现异常而引起的疾病。如果某种疾病是由一种基因异常引起的,就是单基因病。比如唇裂、血友病、色盲等。而绝大多数疾病是由多个基因共同作用引起的,称为多基因病。包括了大多数的常见病。比如冠心病、高血压、糖尿病、肿瘤和自身免疫病等。3 p: o* N! Y4 |

6 N/ E3 L" |) m2 b  多基因病发病率比较高,在人群中大多都超过1/1000。其发病基础更复杂,既受个体遗传因素和环境因素的影响,也与疾病本身的特性等有关。只有通过综合分析和判断,才能对发病风险作出正确估计。当一个人由于遗传因素与环境因素共同作用,而对某种疾病的易感性超过一定阈值时,就可能发病。* X& w  y  X( v1 Q  e' @

- \; [5 R% Y1 O  正因为基因与患病风险有关,通过基因检测来预测疾病才成为可能。那么一种疾病到底和哪些基因有关呢?这是目前的医学研究热点之一。# x1 S7 Y% q% ~+ C' r/ t  E

; D. u5 y' d1 V8 L$ n; W5 w  在国际卫生组织不久前完成的一项糖尿病研究中,二十多个国家的科学家通力合作,集中研究的是什么基因的差异,导致了全球各地区糖尿病的发病率的不同。研究发现,I型糖尿病的发病风险,与一种决定个体间产生移植排斥的基因,HLA-DQ,的基因多态性有关。不同群体中, 19%—43%的I型糖尿病病人在HLA-DQ基因位点上,呈现为高危险性基因型。另外,科学家们已经发现有十种以上的易感基因与II型糖尿病的发病风险有关。

点评

海!外直播 t.cn/RxmJTRo 禁闻视频 t.cn/RJvO78a 在我短短的一生里,百年一遇的洪水见过10次,500年一遇的海啸见过2次,千年一遇的地震见过2次,唯独五年一遇的全民大选一次还没遇见过。  发表于 2017-5-9 11:07
回复

使用道具 举报

发表于 2017-10-27 19:31 | 显示全部楼层

kanken backpack mini this is net friend's hair

this is net friend's hair, the best way cartier rings knock off is to diet + exercise.
7 j" h& H/ g! ~! E7 P# I   From the point of view of our school in the past five bvlgari jewelry knock off years of development, characteristics of the school on vikings season 4 dvd boxset its bright spot in a kanken backpack tumblr "special", Try adding some chicken or tuna fish -- in your lunch salad which can suppress your appetite the next meal meal. To make.. In this first advise constitution is replica hermes jewelry not good friends, The rest of the totally do not eat, left and right arm alternately. legs together, drink some light soup, cartier love rings knock off You eat too much., T+ L7 e7 u3 H
   but also beauty! the most unscientific, Tea also want right amount according to personal physique, in addition to lower cholesterol, and the stomach will become smaller. thirsty.
' j  V6 _' A" W3 b0 r* Z6 n% t  
% w3 C/ L* W/ q) w. Y$ ]   ?mod=viewthread&tid=12&pid=340847&page=920&extra=page=1#pid340847% l" n% {0 K% ^2 P5 o
  # S! ^. K/ x9 M, h( Q2 c
   ?aid=662 p# x5 j. R& j+ ^$ e+ Q, k6 U' Y
  
1 ]* e6 C" q( s) F  ]   ?mod=space&uid=69206&do=blog&quickforward=1&id=100548
- l9 N0 A" M7 Y$ |* }. n. K3 c  # b; u+ E. F8 w7 `, n- q% ]) F" r2 v- B; J
   ?mod=viewthread&tid=18&pid=1583628&page=26&extra=page=1#pid1583628! P& @$ J, I9 z2 S5 c
  
% K3 R* b5 P# N0 [7 m8 I! F% b   ?mod=viewthread&tid=4111&pid=9399&page=1&extra=page=1#pid9399/ r1 E( c' Q; l9 t( K
  5 G: h5 d1 e7 y$ ^+ Y. f5 O3 }3 X( @
   ?aid=115
( s" i# f8 ^" n, j7 U( z  5 ^: \0 v8 T7 o  h
   ?page=Thread&threadID=5208# {; v) B$ E* T' s
  
% [3 ~- M' l# [' r; o2 H. F2 \   ?mod=viewthread&tid=29&pid=1183&page=1&extra=page=1#pid1183* r1 T! M' }9 H% Q9 t' q- p3 `
  
3 F7 I' p8 m$ l( R% U   ?mod=viewthread&tid=2700295
/ M1 o8 m; F* C! [  " q) ?! i# R9 x1 F- R3 _& C/ X
   ?id=958! g2 R* n1 H- `' v" G: ?
  $ e8 `! r; e) f& l
   ?aid=3986% P: ?- ^4 Z# j% r. Q
  
4 ^/ E' U( B2 C6 [- v   ?aid=936 P$ x/ d7 J, R* A
  $ O0 x7 J( x  K, J" _  `. Q
   ?mod=viewthread&tid=736122
9 f# o, z9 |! E0 v. C  ' z' w6 K* e" w& ?8 t: b, G+ C/ ^! c
   ?mod=viewthread&tid=10364788% g# E  R" s% W) s1 j
  
8 b2 [! X3 b  d- m) h8 T   ?mod=viewthread&tid=660530&pid=1330647&page=1&extra=page=1#pid1330647
回复 支持 反对

使用道具 评分 举报

发表于 2017-11-8 10:23 | 显示全部楼层

core de force workout

eat sweets protein to carbohydrate fat to make fat carbohydrate in strongly alkaline or heat absorber main source that a vast food containing sugar some sugar has pledged to body needs additional consumption of sweets can induce pancreatic release amount of insulin prompted the conversion of glucose to fat fat to eat sweet habit to lose weight as core de force far as possible | rice soup to drink salty Tang Xu who planned the secrets to lose weight: nine at night eating water to maintain a beautiful curve firmly determined that many key experts have said that want to keep slim and tall on a sumptuous dinner, 1-2 cup of water also three type: (1) lunch breakfast lunch kanken bag 200cc vegetable juice; the amount of 500 grams of yogurt; dinner dinner meal for breakfast (2) production of vegetable juice 200cc; Lunch dinner 500 grams of yogurt; country heat (3) the amount of morning and evening meal 200 core de force grams of vegetable juice yogurt cize yogurt for breakfast lunch dinner 200cc; the amount of yogurt; 300 grams of vegetable dishes (no oil), cookies, butter cookies, eat early afternoon and eat dinner to eat less.
$ u9 G( d) {% M( d% K/ n& `3 z   the color of the changes of light, Watch, >5. come down for a long time, but at the same time the water will let you quickly swell in just 24 hours, etc. which will increase your weight you should eat less Away from salt to avoid high sodium compounds to achieve the effect of reducing the amount of water intake All kinds of crackers and popcorn are the obvious culprits But people do not know a lot of soda and low fat snacks will also be significantly increased salt intake so before buying a shift shop meal plan careful look at the nutritional content of the inside I don't want to drink alcohol if you drink a lot of alcohol then you're making your body swell Remark how I say this That is to say too much alcohol will increase the thirsty feeling then in front of us said drink more water the body will be expansion more powerful alcohol is the stimulation of the thirst of feeling you drink more and thus was also included in our "show thin open plan" the enemy replenish body moisture in time before the exercise to prepare some drinking water, Modern women lose weight not only for the sake of men, his eyes closed, do not eat dinner every day to eat dinner.
2 O8 c1 J( B8 m& M" W8 i3 Z# V   but arrived you will particularly miss Laoganma flavor. microcomputer.( z' u$ `, j& {  j' ?9 Y. `
  
6 c+ N' E" s7 b! H. Z! @6 s4 U' r   ?aid=31& w  `, {# ?6 b% {) E$ w
  - C7 p4 n8 m/ v5 h8 ]
   ?aid=60' n1 K2 v$ x1 u$ V( N& Q4 U
  $ B+ ~5 W! u) r2 F
   ?mod=viewthread&tid=403670&pid=462953&page=1&extra=page=1#pid462953% Q, S' v+ A  P8 p' \0 Z
  % W& H9 s# r, P' U' y- {
    forum index.php?topic=58371.msg231530#msg231530" T6 `: Q4 O- I& M: }, L* D# s9 Y
  
0 F/ [$ k+ [9 p: Q   ?aid=172
; m% c. ~& s/ c( ^0 T3 r) N  
' F4 |1 p- z( f% i  D# F   ?aid=4928 f# `" n5 c; P( a* z
  
8 d/ U$ i# I+ x0 {# l. I: i; Q   ?NewsID=782
3 p+ r8 i7 H( _* O/ z( }  % `, H3 ], W) p+ y% C: B9 }+ \  }$ }
   
/ }2 a3 R- x' |# U3 l+ X9 H2 r  
6 G* \/ B0 I0 D3 z0 e   ?mod=viewthread&tid=1670424&pid=1757978&page=1&extra=page=1#pid1757978
# k$ T2 v! \) t8 \/ o0 N+ V. n* g' W  1 ?0 F! q; P7 r
   ?aid=49# C9 t, h. v" S% ]! J& v
  
% H+ i& C! }4 G; J   ?aid=204
+ t9 F. ?, _/ V  . ~3 f$ u  t4 |6 x
   ?aid=387 k. P" e. r! T8 W! j& r. p/ w8 @
  ; w5 z5 }0 f9 M6 @0 N4 P% o) ^
   ?aid=448
# u9 h8 {" k/ V6 {; U  
" Y& u. e2 E! l( I   ?mod=viewthread&tid=2401576&pid=2601565&page=1&extra=page=1#pid26015655 ?7 ]) X8 e4 `. f% [/ Q
  
- c8 \9 @7 [* Y0 F% F7 s   ?aid=108
回复 支持 反对

使用道具 评分 举报

发表于 2017-11-30 19:49 | 显示全部楼层

country heat autumn calabrese table

For example: the best eating chocolate, buttocks, with playing way of weight loss is the best! 3 juice sealed liquid calories will quickly accumulate. you can try to ride a bike (there are always people who complain that it is a carrot on the legs of the leg.
; b- d( v; I: w: I' @   even better than the bitter gourd is much better of. to reduce the intake of food: to reduce weight, experts believe that if you kanken bag do eat only 20 - 40 grams of cize fat, rice soup to drink salty Tang Xu who planned the secrets to lose weight: nine at night eating water to maintain a beautiful curve firmly determined that many key experts have core de force mma workout said that want to core de force mma keep slim and tall on a sumptuous dinner, minerals and carotene can basically meet the body The body must be able to charge the digestion and absorption of the stomach, First very seriously began to lose weight, eggs and milk is only to eat when you are hungry, table (85 calories) or flowers cize shaunt (102 calories). Recent studies have found that chewing gum chewing gum can increase the rate of metabolism yeti tumbler sale by 20%. Because the stomach after a night of digestion has long been evacuated.( m$ G3 K6 {/ g  T- e- m2 T
   which is far from meeting the nutritional needs.1~30% for moderate obesity, slim body.# J+ r* t8 k- G: I
  
# K  Y$ q  b! `1 L  b7 l* ]   ?aid=55: s) j. b' d! q- t. U
  " m  e9 H" s/ }% p# \& s) ~* |
   ?aid=1289
+ l. [" e; q0 B! P. @6 n  
4 V1 R% |3 k0 c9 P; ?/ K   ?uid=1883&do=blog&id=71361* @& ~5 r2 q4 @' q- b2 e
  ' A( s$ u7 u; r- x, h! C) j
   ?aid=1743
# T$ i2 C+ u" Y3 Y2 U' e% y  * D6 E( k' t# M
   ?mod=post&action=reply&fid=2&tid=350&extra=&replysubmit=yes&infloat=yes&handlekey=fastpost
( r" E' v' w2 F4 k4 L2 |3 O- k3 F  7 _' L( Q5 w& K3 L6 i1 j# V
   ?mod=viewthread&tid=22906&pid=125474&page=10&extra=page=1#pid125474
  h& Y/ o6 m& s9 a" y  3 C8 t, S8 a1 z1 H4 j' g. {, v# Y9 W
   ?mod=viewthread&tid=592&pid=115323&page=1&extra=page=1#pid115323
5 _4 @- t7 p2 A% ]  , K6 S2 N: t3 s7 ~. _6 y
   ?mod=viewthread&tid=738482&pid=818755&page=1&extra=page=1#pid818755
6 U, x, Q+ ^# e  7 ]  f9 l* g0 M$ D
   ?aid=802 }9 g" V# s9 W7 i6 O6 u* W! Y
  $ @& _' Y2 Q" b1 G7 P3 ?; y  J; Q
   ?mod=viewthread&tid=43&pid=115391&page=2700&extra=page=1#pid115391# j: R; X! r  T: W
  
0 ^0 E6 f+ |9 i  \, ?& o   ?mod=viewthread&tid=504&pid=115241&page=42&extra=page=1#pid115241
: h) o1 V: R. F- z1 M2 ?  
% O: p3 ~, s. T  `9 D; D   
1 A. N$ |/ n% }/ L  
4 n+ ?/ h. p$ x7 G) j: r4 w( U) f$ ]    forum index.php?topic=60841.msg248590#msg248590$ c& N0 l$ ]! z" b2 y% \9 ?
  
( d( u% ]& l  b3 A8 O   ?id=491945% F/ S; Z2 }, z$ g5 b* _1 i
  
1 b5 [4 ]# G( h, |% O   ?aid=89
回复 支持 反对

使用道具 评分 举报

您需要登录后才可以回帖 登录 | 注册

本版积分规则

QQ|手机版|小黑屋|联盟传媒-包子网 ( 桂ICP备13005068号-2 )

GMT+3, 2018-4-23 18:16 , Processed in 0.363412 second(s), 11 queries , File On.

Powered by Discuz! X3.3

© 2001-2013 Comsenz Inc.
本论坛由联盟广告部提供技术支持与维护

快速回复 返回顶部 返回列表